姓名:张玉泉
职称:主任医师/教授
个人简介:江苏南通人,医学博士,妇产科教授,主任医师,博士研究生导师,南通大学附属医院妇产科学科带头人,江苏省妇产科名医。2017年南通市拔尖技术人才,南通市“226工程”第一层次培养人才,全国“2019健康卫士致敬人物奖”荣誉称号。现任江苏省妇科专业质量控制中心主任、中华医学会妇产科分会委员、中国医师协会妇产科医师分会常委、世界华人医师协会妇产科分会常委、江苏省医学会妇产科分会前任主任委员、江苏省医师协会妇产科医师分会会长、中国整形美容协会科技创新与器官整复分会盆底功能障碍性疾病物理康复专业委员会主任委员、江苏省妇幼保健协会妇产科质量控制分会主任委员、中国优生优育协会生育健康与出生缺陷防控专委会副主任委员、江苏省危急重症孕产妇救治指导中心主任、江苏省医学会妇科肿瘤分会副主任委员、江苏省医学会妇产科分会肿瘤学组组长等,国家自然科学基金评审专家,博士后基金评审专家,《现代妇产科进展》等杂志审稿专家。
近年来从事妇产科静脉血栓栓塞症的防治及脐带间充质干细胞对自然流产治疗的基础及临床研究,主持科技部国际合作课题、国家自然基金课题、江苏省社会发展课题、南通市重点病种规范化诊治课题等各级科研课题,获全国妇幼健康自然科技奖、江苏医学科技奖等各级奖项。主编中国科学院教材建设专家委员会规划教材《妇产科学》及《临床肿瘤妇科学》,参编全国留学生双语教材《妇产科学》。发表科研论文150余篇,共培养博士、硕士研究生及留学生100余名。
专业研究领域:妇产科静脉血栓栓塞症,妇科肿瘤,脐带间充质干细胞。
专著与论集:
[1] Xi Cheng, Mu Zhang, Yuanyuan Xie, Yanhua Xu, Rong Du, Bowen Wu, Zongyu Guan, Weina Wang, Weiwei Sun, Ting Xu, Shunxing Zhu, Liucheng Wu, Xu Wang, Hongyun Shi, Baolan Sun, Yuquan Zhang(通讯). Bone marrow-derived mesenchymal stem cells accelerate angiogenesis in pregnant experimentally induced deep venous thrombosis rat model via up-regulation of pro-angiogenic secretogranin II. International Immunopharmacology. 2023 March;118(2023):110025.
[2] Wu X, Zhang K, Zhong X, Huo X, Zhang J, Tian W, Yang X, Zhang Y(通讯), Wang Y. Androgens in endometrial carcinoma: the killer or helper? J Endocrinol Invest. 2023 Mar;46(3):457-464.
[3] Xu Y, Zhang M, Shi Q, Cheng X, Du R, Li C, Zhang Y(通讯). Identification of HOXB9 to predict prognosis of endometrial cancer based on comprehensive bioinformatics analysis. Eur J Med Res. 2023 Feb 17;28(1):79.
[4] Du R, Cheng X, Ji J, Lu Y, Xie Y, Wang W, Xu Y, Zhang Y(通讯). Mechanism of ferroptosis in a rat model of premature ovarian insufficiency induced by cisplatin. Sci Rep. 2023 Mar 17;13(1):4463.
[5] Cheng X, Wang W, Du R, Zhang M, Xie Y, Sun W, Ji J, Sun B, Zhang Y(通讯). Impact of repeated intravenous infusions of umbilical cord-derived versus bone marrow-derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model. In Vitro Cell Dev Biol Anim. 2022 Dec;58(10):957-969.
[6] Cheng X, Sun B, Liu S, Li D, Yang X, Zhang Y(通讯). Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution. Exp Ther Med. 2021 Feb;21(2):142.
[7] Shi Q, Wang D, Ding X, Yang XQ, Zhang YQ(通讯). Exosome-shuttled miR-7162-3p from human umbilical cord derived mesenchymal stem cells repair endometrial stromal cell injury by restricting APOL6, Arch Biochem Biophys, 2021, 707:108887.
[8] Wang H, Yang X, Chen X, Xie H, Wang J, Zhang Y(通讯). Identify the role of Human Wharton's Jelly Mesenchymal Stem Cells in repairing injured uterine of rat. J Obstet Gynaecol Res. 2021 Jan;47(1):320-328.
[9] Shi Q, Gandi DS, Hua Y, Zhu Y, Yao J, Yang X, Xu Y, Zhang Y(通讯). Postpartum septic pelvic thrombophlebitis and ovarian vein thrombosis after caesarean section: a rare case report. BMC Pregnancy Childbirth. 2021 Aug 17;21(1):561.
[10] Shi Qin, Sun Baolan, Wang Di, Zhu Yi, Zhao Xinxin, Yang Xiaoqing, Zhang Yuquan(通讯). Circ6401, a novel circular RNA, is implicated in repair of the damaged endometrium by Wharton's jelly-derived mesenchymal stem cells through regulation of the miR-29b-1-5p/RAP1B axis, Stem Cell Res Ther, 2020,11(1):520.
[11] Gao S, Bian T, Su M, Liu Y, Zhang Y(通讯). miR‑26a inhibits ovarian cancer cell proliferation, migration and invasion by targeting TCF12. Oncol Rep. 2020 Jan;43(1):368-374.
[12] Peng C, Yang Y, Ji L, Yang P, Yang X, Zhang Y(通讯). Cyclin H predicts the poor prognosis and promotes the proliferation of ovarian cancer. Cancer Cell Int. 2020 Jul 16;20:316.
[13] Zhong Y, Wang Y, Huang J, Xu X, Pan W, Gao S, Zhang Y(通讯), Su M. Association of hCG and LHCGR expression patterns with clinicopathological parameters in ovarian cancer. Pathol Res Pract. 2019 Apr;215(4):748-754.
[14] Sun Baolan,Shi Lei,Shi Qin,Jiang Yao, Su Zhangyao, Yang Xiaoqing, Zhang Yuquan(通讯). Circular RNAs are abundantly expressed and upregulated during repair of the damaged endometrium by Wharton’s jelly-derived mesenchymal stem cells, Stem Cell Research & Therapy, 2018, 9(1):314-326.
主要科研项目
近年来从事妇产科静脉血栓栓塞症的防治及脐带间充质干细胞对自然流产治疗的基础及临床研究,主持科技部国际合作课题、国家自然基金课题、江苏省社会发展课题、南通市重点病种规范化诊治课题等各级科研课题。
讲授课程
妇产科学(本科生教学);妇产科学(外国留学生教学);妇产科学进展(硕士生教学);妇科肿瘤新进展(博士生教学)
指导研究生情况
在读博士生4名、硕士生9名,共培养博士、硕士研究生及留学生100余名。